The capital Kiev was hit hardest in the attack, where a ballistic missile struck a nine-story apartment building, killing 14 people and injuring 60 others, Interfax-Ukraine news agency cited the minister as saying.
In the southern city of Odessa, one person was killed and 10 others injured.
Casualties were also reported in the Kiev and Chernihiv regions.
Tymur Tkachenko, head of the Kiev City Military Administration, said Russia launched a total of 175 drones, along with more than 14 cruise missiles and two ballistic missiles at the capital, hitting residential areas.
The Interior Ministry said that 27 locations in Kiev, including apartment buildings, educational institutions and critical infrastructure facilities, were under attack overnight.
Search and rescue operations are ongoing at the sites of the strikes, the State Service for Emergencies said. (Xinhua/NAN)
